| 1 | (2S,2'S)-1,1'-(2,2'-((3-Hydroxyadamantan-1-yl)azanediyl)bis(acetyl))bis(pyrrolidine-2-carbonitrile) | Impurity-D (Dimer impurity) as per IP monograph | 1036959-23-5 | Vildagliptin |
| 2 | N-(2-((S)-2-Cyanopyrrolidin-1-yl)-2-oxoethyl)-N-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)nitrous amide | Vildagliptin nitroso impurity | 3034601-47-0 | Vildagliptin |
| 3 | (R)-8-(3-Aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione | Process impurity | 1791405-13-4 | Linagliptin |
| 4 | 7-(But-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione | Process impurity | 586408-08-4 | Linagliptin |
| 5 | (2R)-1-(2-((3-Hydroxyadamantan-1-yl)amino)acetyl)pyrrolidine-2-carbonitrile | R-Isomer | 1036959-27-9 | Vildagliptin |
| 6 | (S)-8-(3-Aminopiperidin-1-yl)-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-1H-purine-2,6(3H,7H)-dione | S-Isomer | 668270-11-9 | Linagliptin |
| 7 | (S)-N-Valeryl-N-([2'-(1H-tetrazole-5-yl)biphen-5-yl]methyl)-valine methyl ester | Impurity-E (USP)/Methyl ester | 137863-17-3 | Valsartan |
| 8 | (S)-N-Valeryl-N-([2'-(1H-tetrazole-5-yl)biphen-6-yl]methyl)-valine ethyl ester | Ethyl ester impurity | 1111177-30-3 | Valsartan |
| 9 | (S)-N-Valeryl-N-([2'-(1H-tetrazole-5-yl)biphen-7-yl]methyl)-valine isopropyl ester | Iso propyl ester impurity | 1245820-09-0 | Valsartan |
| 10 | (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid | Di acid Impurity/Des ethyl impurity | 149709-44-4 | Sacubitril |
| 11 | (2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate | Di ethyl ester Impurity | 2216747-18-9 | Sacubitril |
| 12 | Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-methoxy-4-oxobutanamido)-2-methylpentanoate | Methyl ethyl ester | 2507643-94-7 | Sacubitril |
| 13 | (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)(nitroso)amino)propyl)-2-methoxybenzenesulfonamide | Tamsulosin Nitrosoamine impurity | 2892260-31-8 | Tamsulosin HCl |
| 14 | N-(2-Hydroxy-3-(4-((2-isopropoxyethoxy)methyl) phenoxy) propyl)-N-isopropylnitrous amide | Bisoprolol Nitrosoamine impurity | 2820170-76-9 | Bisoprolol Fumarate |
| 15 | (2S)-1-[2-[(3-Hydroxytricyclo[3.3.1.13,7]dec-1-yl)amino]acetyl]-2-pyrrolidinecarbonitrile | Vildagliptin (IP) | 274901-16-5 | Vildagliptin |
| 16 | 8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione | Linagliptin | 668270-12-0 | Linagliptin |
| 17 | (1RS)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3-oxo-1,3-dihydro-2-benzofuran-5-carbonitrile (Oxalate salt) | Escitalopram Impurity-C (EP) | 372941-54-3 | Escitalopram |
| 18 | (R)-1-(2-chloroacetyl)pyrrolidine-2-carboxamide | Vildagliptin Chloroacetyl Nitrile (R)-Isomer | 565452-98-4 | Vildagliptin |
| 19 | (S)-1-(2-Chloroacetyl)pyrrolidine-2-carboxamide | Vildagliptin Chloroacetyl Amide Impurity | 214398-99-9 | Vildagliptin |
